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Biography
Dr. Paul M. Ridker

Paul M Ridker, MD, MPH, FACC, FAHA
Eugene Braunwald Professor of Medicine, Harvard Medical School
Director, Center for Cardiovascular Disease Prevention
Divisions of Cardiovascular Diseases and Preventive Medicine
Brigham and Women's Hospital
Boston, Massachusetts

Dr. Ridker is the Eugene Braunwald Professor of Medicine at the Harvard Medical School and directs the Center for Cardiovascular Disease Prevention, a translational research unit at the Brigham and Women's Hospital in Boston which focuses on the molecular and genetic epidemiology of cardiovascular diseases.

As a graduate of Brown University, the Harvard Medical School, and the Harvard School of Public Health, Dr. Ridker's primary research brings together classical tools of large-scale, population based epidemiology with emerging genetic and molecular techniques designed to improve our ability to predict and prevent thrombotic occlusion. Particular areas of interest involve molecular and genetic determinants of hemostasis, thrombosis, and inflammation with a focus on "predictive medicine", early disease diagnosis, and the underlying causes and prevention of acute coronary syndromes. Dr. Ridker's research efforts are supported by multiple RO1 research grants from the National Heart, Lung, and Blood Institute (NHLBI) as well a Distinguished Clinical Scientist Award from the Doris Duke Charitable Foundation.

Dr. Ridker is also the Principal Investigator of PREVENT, an NHLBI-funded multi-center clinical trial of thrombosis prevention among individuals with and without genetic predispositions to hypercoagulability. Dr. Ridker additionally directs an NHLBI-funded institutional National Research Service Award (training grant) in cardiovascular epidemiology, and Co-Directs the Leducq Center for Cardiovascular Research at the Brigham and Women's Hospital and Harvard Medical School. Dr. Ridker has been the recipient of both a Clinician Scientist Award (1992-1997) and an Established Investigator Award (1997-2002) from the American Heart Association. A frequent invited lecturer at national and international conferences, Dr. Ridker lists among his honors elected membership into the American Society for Clinical Investigation (ASCI), the American Epidemiological Society (AES), and the American Association of Physicians (AAP). Citing his pioneering work on inflammation, C-reactive protein (CRP), and atherothrombosis, Time Magazine honored Dr. Ridker as one of America's Ten Best Researchers in Science and Medicine in 2001. In 2003, Dr. Ridker's work on inflammation and CRP lead to the first set of federal guidelines advocating CRP evaluation as a new method for cardiovascular disease detection. Also in 2003, Dr. Ridker was named as a Reynolds Investigator and as Co-Director of the Reynolds Center for Cardiovascular Research at the Harvard Medical School.

Dr. Ridker is the author of over 190 original reports, 90 reviews and book chapters, and 3 textbooks related to cardiovascular medicine. Dr. Ridker serves on the editorial board of several major journals and is a Consulting Editor for Circulation.

Dr. Ridker is listed as a co-inventor on several patents filed by the Brigham and Women's Hospital that relate to the use of inflammatory biomarkers in cardiovascular disease.

Presentations by Dr. Paul M. Ridker that are available on CRPhealth.com
CRP, Statins, and Coronary Risk: Why the JUPITER Trial?
2004-03-30

CRP, Inflammation, and its Relationship to Cardiovascular Disease, Metabolic Syndrome and Type 2 Diabetes
2004-04-03

An Introduction to High-Sensitivity C-Reactive Protein (hs-CRP) for Patients: Can We Better Predict Heart Attack and Stroke?
2004-10-13

C-Reactive Protein (hsCRP), Inflammation, and Cardiovascular Risk: Why the VAL-MARC Trial?
2004-10-13

Do patients on statin therapy need hsCRP measured? Update January 2005
2005-01-31

Should We Measure hsCRP After Starting Statin Therapy? Update 2005
2005-01-31

Non-HDL Cholesterol, Apolipoproteins A-1 and B-100, Standard Lipid Measures, Lipid Ratios, and CRP as Risk Factors for Cardiovascular Disease in Women
2005-08-09

Valsartan, Blood Pressure Reduction, and C-Reactive Protein: Primary Report of the Val-MARC Trial
2006-05-18

Prediction and Prevention: Where might hsCRP Fit In?
2006-10-04

Use of Surrogate Outcomes, Surrogate Endpoints, and Biomarkers in Randomized Clinical Trials of Cardiovascular Disease: Does hsCRP Have A Role
2006-10-04

Blood Pressure, Blood Pressure Therapy, and C-Reactive Protein (hsCRP): A Patient Based Update
2006-10-04

Should I Use Biomarkers in Assessing Cardiovascular Risk? Where did we start, where are we now, and where are we going?
2006-11-12

A Comparison of hsCRP and Lp-PLA2 as Biomarkers to Assist in the Detection and Treatment of Cardiovascular Disease
2007-03-24

How to Predict Your Risk of Heart Attack or Stroke: The Reynolds Risk Score - Bringing hsCRP and Genetics to Clinical Practice
2007-03-27

LDL-C vs hsCRP vs HDL-C: What is the Primary Driver of Benefit?
2007-12-04

Inflammation and Novel Risk Markers – From Acute Coronary Syndromes to Primary Prevention
2007-12-04

Genetic Determinants of Inflammation: Focus on CRP
2008-08-14

The JUPITER Trial Results - A Randomized Trial of Rosuvastatin in the Prevention of Cardiovascular Events Among 17,802 Apparently Healthy Men and Women With Elevated Levels of C-Reactive Protein (hsCRP)
2008-11-09


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