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The Jupiter Trial slides results

Rosuvastatin in the Primary Prevention of Cardiovascular Events Among Individuals With Low Levels of Low-Density Lipoprotein Cholesterol and Elevated High-Sensitivity C-Reactive Protein


Latest Online Presentations Jan 4
Your source on C-Reactive Protein
CRP Reduction, LDL Reduction, and Cardiovascular Event Rates After Initiation of Rosuvastatin: The JUPITER Trial
Dr. Paul M. Ridker

Dr Ridker discusses new findings from the JUPITER trial which were initially released at the American College of Cardiology meeting in March 09. As was previously reported in the New England Journal of Medicine, treatment with rosuvastatin significantly reduced vascular event rates in individuals with normal levels of LDL cholesterol...

Your source on C-Reactive Protein
Clinical Application of C-Reactive Protein Across the Spectrum of Acute Coronary Syndromes
Dr. Benjamin Scirica

High hsCRP levels have been found to be associated with poor cardiovascular outcomes in patients with acute coronary syndrome (ACS). There are however few data and some conflicting data with regards to ST elevation MI, the full spectrum of ACS, specific subgroups of patients with ACS, and the timing of measurement of CRP. The purpose of the...

Your source on C-Reactive Protein
Favorable effect of statins on local inflammatory activation in non-culprit lesions of patients with multivessel coronary artery disease
Dr. Konstantinos Toutouzas

Recently, new insights have become available into how anti-inflammatory effects of statin treatment impact on what happens within the coronary arteries. As seen in the REVERSAL trial, for example, a reduction in systemic inflammation, as indicated by the level of C-reactive protein, was important in addition to cholesterol-lowering, for the...

Your source on hs-CRP testing




Latest Publications Jan 11
CRP publications of broad clinical interest View All

Development and Validation of Improved Algorithms for the Assessment of Global Cardiovascular Risk in Women: The Reynolds Risk Score

Author : Ridker PM et al.
2007-02-14JAMA

This article describes how the Reynolds Risk Score was developed and validated using data from 24,558 initially healthy American women, who were followed up for a median of 10.2 years for incident cardiovascular events.

Clinical Relevance of C-Reactive Protein During Follow-Up of Patients With Acute Coronary Syndromes in the Aggrastat-to-Zocor Trial

Author : David A. Morrow
2006-08-01Circulation

New data from almost 4000 patients with ACS demonstrating the clinical utility of hs-CRP measured at 30 days or 4 months of follow-up, in terms of predicting 2-year mortality.

CRP and cardiovascular disease publications View All

Rosuvastatin in the Prevention of Stroke Among Men and Women With Elevated Levels of C-Reactive Protein - Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER)

Author : Brendan M. Everett
2010-01-05Circulation

Black tea reduces uric acid and C-reactive protein levels in humans susceptible to cardiovascular diseases.

Author : Bahorun T
2009-12-18Toxicology
CRP and hypertension publications View All

Relation of Left Ventricular Hypertrophy With Systemic Inflammation and Endothelial Damage in Resistant Hypertension

Author : Gil F. Salles
2007-07-16Hypertension

C-Reactive Protein and Incident Left Ventricular Hypertrophy in Essential Hypertension

Author : Farahnak Assadi
2007-07-12Pediatric Cardiology
CRP and hsCRP testing View All

Health screening packages: the place of measuring C-reactive protein.

Author : Wong MS.
2006-10-20PubMed

Should high sensitive C-reactive protein measurement be included in health screening packages?

Author : Hawkins RC, Leong L.
2006-10-06PubMed
CRP and diabetes publications View All

Association of inflammation with worsening HOMA-insulin resistance.

Author : Park K
2009-08-13Diabetologia

C-reactive protein (CRP) up-regulates expression of receptor for advanced glycation end products (RAGE) and its inflammatory ligand EN-RAGE in THP-1 cells: Inhibitory effects of atorvastatin

Author : Nitin Mahajan
2009-02-05International Journal of Cardiology
CRP and metabolic syndrome publications View All

Reduced high-molecular weight adiponectin and elevated hsCRP are synergistic risk factors for metabolic syndrome in a large scale middle-aged to elderly population: the J-SHIPP study

Author : Yasuharu Tabara
2008-01-13The Journal of Clinical Endocrinology & Metabolism

High-sensitivity C-reactive protein predicts target organ damage in Chinese patients with metabolic syndrome

Author : Zhao Z
2007-11-16Metabolism
CRP and stroke publications View All

High-Sensitivity C-Reactive Protein and Soluble CD40 Ligand as Indices of Inflammation and Platelet Activation in 880 Patients With Nonvalvular Atrial Fibrillation. Relationship to Stroke Risk Factors, Stroke Risk Stratification Schema, and Prognosis

Author : Gregory Y.H. Lip
2007-03-05Stroke

C-Reactive Protein, Carotid Atherosclerosis, and Cerebral Small-Vessel Disease

Author : Reinhold Schmidt, MD; Helena Schmidt, MD, PhD; Martin Pichler, MD; Christian Enzinger, MD; Katja Petrovic, PhD, MSc; Kurt Niederkorn, MD; Susanna Horner, MD; Stefan Ropele, PhD; Norbert Watzinger, MD;
2006-12-01Stroke
CRP and other inflammatory conditions publications View All

Prospective Study of High-Sensitivity C-Reactive Protein as a Determinant of Mortality: Results from the MONICA/KORA Augsburg Cohort Study, 19841998

Author : Wolfgang Koenig
2008-01-13Clinical Chemistry

High-sensitivity C-reactive protein is an independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the severity of fibrosis in NASH

Author : Masato Yoneda
2007-07-26Journal of Gastroenterology
General press news View All

New Findings From JUPITER Show Rosuvastatin Cuts Stroke Risk in Half Among Those With Elevated CRP Levels and Commonly Acceptable Cholesterol Levels

2010-01-09HealthCanal.com

FDA Panel Backs Statin for Primary Prevention

Author : Peggy Peck
2009-12-15MedPage Today

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Latest Publications
Rosuvastatin in the Prevention of Stroke Among Men and Women With Elevated...
Author : Brendan M. Everett
Circulation, 2010-01-05

Black tea reduces uric acid and C-reactive protein levels in humans...
Author : Bahorun T
Toxicology, 2009-12-18

Higher Level of Systemic C-Reactive Protein Is Independently Predictive of...
Author : Straczek C,
J Am Geriatr Soc, 2009-12-18

Insulin resistance is associated with C-reactive protein independent of...
Author : Chou HH
Metabolism, 2009-12-18

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